The profile for a computer is stored in an .ini file. By default, this file is called opscenter.ini and is stored in the OpsCenter program folder. Simply delete this file and OpsCenter will run the profile setup the next time it starts. The file name and location is also listed in the preferences window. Starting in OpsCenter 3.4.0, you can also select disconnect from the File menu and then select Clear user profile from the File menu.